Rajesh Sreedharan Nair

Contact

• workRoom BB76 Building B
  Malaysia Campus
  Jalan Broga
  43500 Semenyih
  Selangor Darul Ehsan
  Malaysia
• work+6 (03)89248681
• Rajesh.Nair@nottingham.edu.my

Biography

Dr. Rajesh is an Associate Professor at the School of Pharmacy, University of Nottingham Malaysia. He is a pharmacist by profession and specializes in pharmaceutics and drug delivery. He has many years of academic experience in both national and international universities. Prior to joining Nottingham Malaysia, he was affiliated with Monash University Malaysia. In recognition of his teaching dedication, he has been honored with multiple teaching excellence awards. He has strong connections with both local and international pharmaceutical companies and is involved in collaborative research projects.

Expertise Summary

Development of nanoformulations for chronic diseases

Topical/Transdermal Drug Delivery

Development of cosmetic/nutraceutical formulations

Development of Oral Controlled Release Drug Delivery Systems

Drug disposition and Pharmacokinetics

HPLC/UHPLC method development and validation

Teaching Summary

PHAR3032- Advanced Drug Delivery

PHAR2056- Pharmaceutics 2: Pharmaceutical Technology

PHAR1027- Pharmaceutics 1: Physicochemical Science and Medicines Design

Research Summary

Mechanism governing the influence of pharmaceutical wastes on water retention and hydraulic conductivity of clays - Co-investigator FRGS 2023.

Evaluation of Ginkgo biloba nanoformulation for improving the bioavailability of extracts .

Extemporaneous stability studies of selected pharmaceutical formulations.

Recent Publications

• SWATHY, K. K., SARATH CHANDRAN, C., MUKUNDAN, MINIL, SREEJITH, K. R., SOURAV, K., JAFNA, M. C., MUKUND, ABHILA V., KAPPALLY, SHIJINA, NAIR, RAJESH SREEDHARAN and JOSEPH, JIM, 2023. Optimised neem oil-bilayer tablets: A safe, effective and stable tool for the prevention of vector-borne disease outbreaks by Aedes albopictus: Experimental Parasitology Experimental Parasitology. 251, 108550
• RAJ, ALAN, DUA, KAMAL, NAIR, RAJESH SREEDHARAN, SARATH CHANDRAN, C. and ALEX, ANGEL TREASA, 2023. Transethosome: An ultra-deformable ethanolic vesicle for enhanced transdermal drug delivery: Chemistry and Physics of Lipids Chemistry and Physics of Lipids. 255, 105315
• MATHEW, AM, BHUVANENDRAN, S, NAIR, RS and K RADHAKRISHNAN, A, 2023. Exploring the anti-inflammatory activities, mechanism of action and prospective drug delivery systems of tocotrienol to target neurodegenerative diseases [version 1; peer review: 1 approved, 1 approved with reservations]: F1000Research F1000Research. 12(338),
• KK, SWATHY, C, SARATH CHANDRAN, K, SOURAV, KR, SREEJITH, MC, JAFNA, PN, SAJITH KUMAR, KAPPALLY, SHIJINA, NAIR, RAJESH SREEDHARAN and JOSEPH, JIM, 2023. Development and Characterisation of an Optimised Toothpaste of Achyranthes aspera plant extract for the Effective Protection from Dental Black Stain forming Chromogenic bacteria species: South African Journal of Botany South African Journal of Botany. 154, 46-55

• View all publications

Past Research

Development and evaluation of tocotrienol nanoformulations for enhanced transdermal permeation (Monash University Malaysia SEED research grant)- Principal Investigator.

Monash University Malaysia Cross-disciplinary research grant, Methotrexate Stability, Sterility and Shelf-Life in Prefilled Sample Syringe- Co-investigator.

Monash University Malaysia Pilot research grant, Linagliptin-Loaded Nanostructured Lipid Carriers: Development, Optimisation and Stability Evaluation- Co-investigator.

UCSI University Pioneer Scientist Incentive Fund, Formulation and Clinical Evaluation of natural compounds containing Skin Cleanser, Exfoliator and Toner- Principal Investigator.

UCSI University Pioneer Scientist Incentive Fund, Formulation and Clinical Evaluation of natural compounds containing Shampoo and conditioner for Anti-hair fall and Anti-dandruff effects - Co-investigator.

• SWATHY, K. K., SARATH CHANDRAN, C., MUKUNDAN, MINIL, SREEJITH, K. R., SOURAV, K., JAFNA, M. C., MUKUND, ABHILA V., KAPPALLY, SHIJINA, NAIR, RAJESH SREEDHARAN and JOSEPH, JIM, 2023. Optimised neem oil-bilayer tablets: A safe, effective and stable tool for the prevention of vector-borne disease outbreaks by Aedes albopictus: Experimental Parasitology Experimental Parasitology. 251, 108550
• RAJ, ALAN, DUA, KAMAL, NAIR, RAJESH SREEDHARAN, SARATH CHANDRAN, C. and ALEX, ANGEL TREASA, 2023. Transethosome: An ultra-deformable ethanolic vesicle for enhanced transdermal drug delivery: Chemistry and Physics of Lipids Chemistry and Physics of Lipids. 255, 105315
• MATHEW, AM, BHUVANENDRAN, S, NAIR, RS and K RADHAKRISHNAN, A, 2023. Exploring the anti-inflammatory activities, mechanism of action and prospective drug delivery systems of tocotrienol to target neurodegenerative diseases [version 1; peer review: 1 approved, 1 approved with reservations]: F1000Research F1000Research. 12(338),
• KK, SWATHY, C, SARATH CHANDRAN, K, SOURAV, KR, SREEJITH, MC, JAFNA, PN, SAJITH KUMAR, KAPPALLY, SHIJINA, NAIR, RAJESH SREEDHARAN and JOSEPH, JIM, 2023. Development and Characterisation of an Optimised Toothpaste of Achyranthes aspera plant extract for the Effective Protection from Dental Black Stain forming Chromogenic bacteria species: South African Journal of Botany South African Journal of Botany. 154, 46-55
• NAIR, RAJESH S, BILLA, NASHIRU and MORRIS, ANDREW, 2022. A validated reverse-phase high performance liquid chromatography (RP-HPLC) method for the quantification of gamma-tocotrienol in tocotrienol rich fractions of crude palm oil: Current Nutrition & Food Science Current Nutrition & Food Science. 18(1), 75-81
• NAIR, RAJESH SREEDHARAN, BILLA, NASHIRU, MOOI, LIM YANG and MORRIS, ANDREW P., 2022. Characterization and ex vivo evaluation of curcumin nanoethosomes for melanoma treatment: Pharmaceutical Development and Technology Pharmaceutical Development and Technology. 27(1), 72-82
• LOK, K. H., WAREHAM, N. J., NAIR, R. S., HOW, C. W. and CHUAH, L. H., 2022. Revisiting the concept of incretin and enteroendocrine L-cells as type 2 diabetes mellitus treatment: Pharmacol Res Pharmacol Res. 180, 106237
• FAIRUZ, SHADREEN, NAIR, RAJESH SREEDHARAN and BILLA, NASHIRU, 2022. Orally Administered Amphotericin B Nanoformulations: Physical Properties of Nanoparticle Carriers on Bioavailability and Clinical Relevance: Pharmaceutics Pharmaceutics. 14(9), 1823
• SREEDHARAN NAIR, R., RAHMAN, H., KONG, M. X., TAN, X. Y., CHEN, K. Y. and SHANMUGHAM, S., 2021. Development and Rheological Evaluation of DEET (N,N-DiethyL-3-Methylbenzamide) Microparticles Loaded Hydrogel For Topical Application: Turk J Pharm Sci Turk J Pharm Sci. 18(3), 352-359
• NAIR, RAJESH SREEDHARAN, BILLA, NASHIRU, LEONG, CHEE-ONN and MORRIS, ANDREW P., 2021. An evaluation of tocotrienol ethosomes for transdermal delivery using Strat-M® membrane and excised human skin: Pharmaceutical Development and Technology Pharmaceutical Development and Technology. 26(2), 243-251
• I. SINGH, R.S. NAIR, S. GAN, V. CHEONG and A. MORRIS, 2019. An evaluation of crude palm oil (CPO) and tocotrienol rich fraction (TRF) of palm oil as percutaneous permeation enhancers using full-thickness human skin Pharmaceutical Development and Technology. 24(4), 448-454
• NAIR, RAJESH SREEDHARAN, MORRIS, ANDREW, BILLA, NASHIRU and LEONG, CHEE-ONN, 2019. An Evaluation of Curcumin-Encapsulated Chitosan Nanoparticles for Transdermal Delivery: AAPS PharmSciTech AAPS PharmSciTech. 20(2), 69
• MANICKAM, BALAMURUGAN, SREEDHARAN, RAJESH and CHIDAMBARAM, KUMARAPPAN, 2019. Drug/Vehicle Impacts and Formulation Centered Stratagems for Enhanced Transdermal Drug Permeation, Controlled Release and Safety: Unparalleled Past and Recent Innovations-An Overview: Current Drug Therapy Current Drug Therapy. 14(3), 192-209
• SINGH, INDERJEET, NAIR, RAJESH SREEDHARAN, GAN, SUYIN, CHEONG, VICTOR and MORRIS, ANDREW, 2019. An evaluation of crude palm oil (CPO) and tocotrienol rich fraction (TRF) of palm oil as percutaneous permeation enhancers using full-thickness human skin: Pharmaceutical Development and Technology Pharmaceutical Development and Technology. 24(4), 448-454
• NAIR, RAJESH SREEDHARAN, MORRIS, ANDREW, BILLA, NASHIRU and LEONG, CHEE-ONN, 2019. An Evaluation of Curcumin-Encapsulated Chitosan Nanoparticles for Transdermal Delivery: AAPS PharmSciTech AAPS PharmSciTech. 20(2), 69
• RAJU Y, PRASANNA, N, HYNDAVI, CHOWDARY V, HARINI, NAIR, RAJESH S., BASHA D, JAMAL and N, TEJESWARI, 2017. In vitro assessment of non-irritant microemulsified voriconazole hydrogel system: Artificial Cells, Nanomedicine, and Biotechnology Artificial Cells, Nanomedicine, and Biotechnology. 45(8), 1539-1547
• SREEDHARAN NAIR, RAJESH and NAIR, SUJITH, 2015. Permeation Studies of Captopril Transdermal Films Through Human Cadaver Skin: Current Drug Delivery Current Drug Delivery. 12(5), 517-523
• TAN WEE NIE, MOHAMED SALEEM ABDUL SHUKKOOR, RAJESH SREEDHARAN NAIR, FATIMAH KHURSIAH BINTI AMIRUDDIN and SHAMALA RAMASAMY, 2015. Involvement of opioidergic and serotonergic systems in the analgesic activity of Cissus quadrangularis L. stem extract in mice: Journal of Basic and Clinical Physiology and Pharmacology Journal of Basic and Clinical Physiology and Pharmacology. 26(1), 35-41
• MANICKAM, BALAMURUGAN, SREEDHARAN, RAJESH and ELUMALAI, MANOGARAN, 2014. ‘Genipin’ – The Natural Water Soluble Cross-linking Agent and Its Importance in the Modified Drug Delivery Systems: An Overview: Current Drug Delivery Current Drug Delivery. 11(1), 139-145
• NAIR, RAJESH SREEDHARAN, LING, TAI NYET, ABDUL SHUKKOOR, MOHAMED SALEEM and MANICKAM, BALAMURUGAN, 2013. Matrix type transdermal patches of captopril: Ex vivo permeation studies through excised rat skin: Journal of Pharmacy Research Journal of Pharmacy Research. 6(7), 774-779
• BEHIN SUNDARA RAJ, SHANTHI, RAJESH SREEDHARAN NAIR, PUNITHA ISAAC SAMRAJ, VIDYA, 2013. Formulation and Evaluation of Coated Microspheres for Colon Targeting ement: 1.