University of Nottingham Malaysia
School of Pharmacy

Image of Siu Yee New

Siu Yee New

Associate Professor,


  • workRoom B1A05 B1-block
    Malaysia Campus
    Jalan Broga
    43500 Semenyih
    Selangor Darul Ehsan
  • work+6 (03) 8924 8762


Dr New Siu Yee received her BSc from University of Technology Malaysia (UTM) and her PhD from National University of Singapore (NUS). During her PhD study, she was involved in multidisciplinary fields of study with three different research groups and spent a year attachment at University of Illinois at Urbana-Champaign (UIUC). After graduated, Dr New worked as Scientist I in Institute Materials Research and Engineering (IMRE), A*Star, Singapore, before joining the University of Nottingham Malaysia. Her current research interest focuses on nanotechnology based biosensors.

Personal research webpage:

Expertise Summary

  • Crystallization techniques for both small molecules and proteins.
  • Various characterization techniques: UV-vis, FTIR, 1D and 2D NMR, electron paramagnetic resonance (EPR), powder X-ray Diffraction (XRD), electrospray ionization-mass spectroscopy (ESI-MS), circular dichroism (CD), spectrofluorometer, surface plasmon resonance (SPR-Biacore), quartz crystal microbalance (QCM), dynamic light scattering (DLS), cyclic voltammetry (CV), thermal gravimetric analysis (TGA), etc.
  • Experience in polymerase chain reaction (PCR), protein expression and purification (fast protein liquid chromatography-FPLC),
  • Experience in handling Schlenk line, TLC, column chromatography, Soxhlet extraction and vacuum liquid chromatography (VLC).
  • Experience in simple modeling using Visual Molecular Dynamic (VMD).

Teaching Summary

MPharm Year 1:

  • Essential Skills of Pharmacists (PHAR1010)

MPharm Year 2 - Year Head:

  • Gastrointestinal & Liver Disorder (PHAR2016) - Module convenor
  • Cardiovascular (PHAR2018)
  • Sexual Health and Pregnancy (PHAR2020)
  • Renal and Endocrine Diseases (PHAR2019)

MPharm Year 3 Research Project - Module convenor

PHS Year 3:

  • Medicinal Chemistry & Drug Design (PHAR3014)

PHS Year 2:

  • Pharmaceutical Analysis & Spectroscopy (PHAR2010)
  • Concepts in Medicinal Chemistry & Drug Discovery (PHAR2014) - Module convenor

PHS Year 1:

  • Laboratories Studies Pharmaceutical Science (PHAR1022)
  • Pharmaceutical & Biological Chemistry 1 (PHAR1008)

Research Summary

Principal Investigator/ Main Applicant (UNM)

2019 - 2021: Facile and PCR-Free Detection of miRNA Using Magnetic Separation and Fluorescent Silver Nanoclusters (Fundamental Research Grant Scheme (FRGS), Ministry of Education (MOE))

2018: SERS Analysis on Reverse Aggregation Control of Cysteamine Coated Gold Nanoparticles (Royal Society of Chemistry; Mobility Grant)

2015 - 2017: Novel Colorimetric & Fluorogenic Nanobiosensors for Telomerase Activity Detection (FRGS, MOE)

2014 - 2015: Systematic Preparation of New Fluorogenic Silver Nanoclusters for Sensing Application (UNMC pump-priming project)


2021 - 2023: Synthesis of protein gold nanoclusters for delivery of silencing-RNA as synergistic colorectal cancer therapy and in situ bioimaging (FRGS, MOE)

2020 - 2021: Colourimetric Nanosensor for the Detection of Ovarian Cancer Biomarker miRNA-665 (MAKNA Cancer Research Award 2020)

2019 - 2020: Detection of Breast Cancer Biomarker miRNA-155 Using Hybridisation Chain Reaction and Silver Nanoclusters (Taylor's University Emerging Research Grant)

2017 - 2019: Elucidation graphene antimicrobial properties against intracellular Staphyloccoccus aureus from bovine mastitis (FRGS, MOE)

2016 - 2019: Development of Multimode "Turn-On" Protein-Gold Nanoclusters for Targeted Theranostics and Imaging of Colon Cancer and Its Metastases (FRGS, MOE)

Selected Publications

  • NEW SIU YEE, CHEUNG EDWIN and SU XIAO DI, 2013. A Method to screen small ligands and determine protein-ligand interactions (Singapore Patent) 201303835-1 05/16/2013 00:00:00
  • NEW SIU YEE, SU XIAO DI and TAN YEN NEE, 2013. Protein-Based Fluorescent Metal Nanoclusters for Drug Screening (Singapore Patent) 201306645-1 09/01/2013 00:00:00
  • STEVEN LUKMAN, NEW SIU YEE, CHEUNG EDWIN and SU XIAO DI, 2013. A Hybrid Sensor using Metal Nanoparticles and Conjugated Polymers (Singapore Patent) 201303638-9 05/10/2013 00:00:00
  • KE LIN, LIM WAI KWAN, NEW SIU YEE, SU XIAO DI and LIU BIN, 2013. Immunosensor Characterization Using Impedance Spectroscopy Journal of Biosensors & Bioelectronics. 4(4),

Past Research

Co-Principal Investigator (IMRE, Singapore)

2012 - 2013: Development of biogenic fluorescent metal nanoclusters for biosensing and clinical diagnosis (IMRE core funded project)

Scientist I (IMRE, Singapore)

2012 - 2013: Integrative analysis of the ongogenic transcription factors, AP-2γ and FoxA1 in breast cancer using nanobiotechnology and genome biology (A*Star JCO funded project)

2011 - 2012: Heterogeneous phase displacement immunoassays for urinary protein markers (Industrial project: IMRE - Nitto Denko Asia Technical Centre Pte. Ltd)

PhD (NUS, Singapore)

2007 - 2011: Supramolecular chemistry and crystal engineering of amino acid Schiff bases

2009 - 2010: Study the effect of site-directed mutagenesis on copper metalloprotein and protein crystallization (University of Illinois, Urbana-Champaign, USA)

Future Research

Please visit our group webpage:

School of Pharmacy

University of Nottingham Malaysia
Jalan Broga, 43500 Semenyih
Selangor Darul Ehsan

telephone: +6 (03) 8924 8000
fax: +6 (03) 8924 8018

Make an enquiry