YIN-YING MAK, BI-JUIN LOONG, PAUL MILLNS, CLAUDIA C. BAUER, ROBIN S. BON, YVONNE MBAKI, FONG-KAI LEE, KUAN-HON LIM, CIN KONG and SUE-MIAN THEN, 2022. Schwarzinicine A inhibits transient receptor potential canonical channels and exhibits overt vasorelaxation effects Phytotherapy Research. 1-12 PANG, LI-YIN, LEE, MEI-KEE, KONG, BOON HONG, FUNG, SHIN-YEE, NG, SZU TING, TAN, CHON SENG, THEN, SUE-MIAN, LIM, KUAN-HON, ROBERTS, RICHARD and TING, KANG-NEE, 2022. Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycota), Cold-Water Extract Relaxes the Rat Isolated Bladder INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS. 24(3), 1-14
CHO, EUN-SEON, KRISHNAN, PREMANAND, LOH, HWEI-SAN, DALY, JANET M., LEONG, CHEE-ONN, MAI, CHUN-WAI, LOW, YUN-YEE, YONG, KIEN-THAI and LIM, KUAN-HON, 2022. Pentacyclic and hexacyclic cucurbitacins from Elaeocarpus petiolatus PHYTOCHEMISTRY. 193,
MAK, YIN-YING, LOONG, BI-JUIN, MILLNS, PAUL, BAUER, CLAUDIA C., BON, ROBIN S., MBAKI, YVONNE, LEE, FONG-KAI, LIM, KUAN-HON, KONG, CIN, THEN, SUE-MIAN and TING, KANG-NEE, 2022. Schwarzinicine A inhibits transient receptor potential canonical channels and exhibits overt vasorelaxation effects PHYTOTHERAPY RESEARCH. JING YING YAP, CHING LIK HII, SZE PHENG ONG, KUAN HON LIM, FARIDAH ABAS and KAR YONG PIN, 2021. Quantification of Carpaine and Antioxidant Properties of Extracts from Carica Papaya Plant Leaves and Stalks Journal of Bioresources and Bioproducts. LEE, FONG-KAI, KRISHNAN, PREMANAND, MUHAMAD, AZIRA, LOW, YUN-YEE, KAM, TOH-SEOK, TING, KANG-NEE and LIM, KUAN-HON, 2021. Concise synthesis of the vasorelaxant alkaloids schwarzinicines A and B NATURAL PRODUCT RESEARCH. CHAN, ZI-YANG, KRISHNAN, PREMANAND, MODARESI, SAYED MOHAMMADHOSSEIN, HII, LING-WEI, MAI, CHUN-WAI, LIM, WEI-MENG, LEONG, CHEE-ONN, LOW, YUN-YEE, WONG, SOON-KIT, YONG, KIEN-THAI, LEONG, ALYSSA ZI-XIN, LEE, MEI-KEE, TING, KANG-NEE and LIM, KUAN-HON, 2021. Monomeric, Dimeric, and Trimeric Tropane Alkaloids from Pellacalyx saccardianus JOURNAL OF NATURAL PRODUCTS. 84(8), 2272-2281 CHAN, ZI-YANG, KRISHNAN, PREMANAND, HII, LING -WEI, MAI, CHUN-WAI, LEONG, CHEE-ONN, LOW, YUN-YEE, WONG, SOON-KIT, TING, KANG-NEE, YONG, KIEN -THAI and LIM, KUAN-HON, 2021. Unusual diarylheptanoid-phenylpropanoid adducts and diarylheptanoid alkaloids from Pellacalyx saccardianus PHYTOCHEMISTRY LETTERS. 46, 36-44
KRISHNAN, PREMANAND, LEE, FONG-KAI, YAP, VERONICA ALICIA, LOW, YUN-YEE, KAM, TOH-SEOK, YONG, KIEN-THAI, TING, KANG-NEE and LIM, KUAN-HON, 2020. Schwarzinicines A-G, 1,4-Diarylbutanoid-Phenethylamine Conjugates from the Leaves of Ficus schwarzii. Journal of natural products. 83(1), 152-158 YAP, JING Y, HII, CHING L, ONG, SZE P, LIM, KUAN H, ABAS, FARIDAH and PIN, KAR Y, 2020. Effects of drying on total polyphenols content and antioxidant properties of Carica papaya leaves Journal of the Science of Food and Agriculture. 100(7), 2932-2937 YEAP, JOANNE SOON-YEE, TAN, CHUN-HOE, YONG, KIEN-THAI, LIM, KUAN-HON, LIM, SIEW-HUAH, LOW, YUN-YEE and KAM, TOH-SEOK, 2020. Macroline, talpinine, and sarpagine alkaloids from Alstonia penangiana. An NMR-based method for differentiating between A. penangiana and A. macrophylla PHYTOCHEMISTRY. 176, ALHUTHALI, HAYAA MOEED, BRADSHAW, TRACEY D., LIM, KUAN-HON, KAM, TOH-SEOK and SEEDHOUSE, CLAIRE H., 2020. The natural alkaloid Jerantinine B has activity in acute myeloid leukemia cells through a mechanism involving c-Jun BMC CANCER. 20(1), PANG, L.Y., TAN, C.S., NG, S.T., LIM, K.H., THEN, S.M. and TING, K.N., 2020. Ophiocordyceps sinensis: a prominent source of bioactive components for alleviating overactive bladder Life Sciences, Medicine and Biomedicine. 4(9), 67 ZI-YANG CHAN, KAYATRIGOVINDARAJU, PREMANAND KRISHNAN, YUN-YEE LOW, KAM-WENG CHONG, KIEN-THAI YONG, KANG-NEE TING and KUAN-HON LIM, 2019. Diphenethylpiperidine alkaloids with tracheal smooth muscle relaxation activity from Hippobroma longiflora (L.) G. Don Phytochemsitry Letters. 30, 93-98 YEAP, JOANNE SOON-YEE, LIM, KUAN-HON, YONG, KIEN-THAI, LIM, SIEW-HUAH, KAM, TOH-SEOK and LOW, YUN-YEE, 2019. Lycopodium Alkaloids: Lycoplatyrine A, an Unusual Lycodine-Piperidine Adduct from Lycopodium platyrhizoma and the Absolute Configurations of Lycoplanine D and Lycogladine H JOURNAL OF NATURAL PRODUCTS. 82(2), 324-329 KRISHNAN, PREMANAND, MAI, CHUN-WAI, YONG, KIEN-THAI, LOW, YUN-YEE and LIM, KUAN-HON, 2019. Alstobrogaline, an unusual pentacyclic monoterpenoid indole alkaloid with aldimine and aldimine-N-oxide moieties from Alstonia scholaris TETRAHEDRON LETTERS. 60(11), 789-791 EZEOKE, M.C., KRISHNAN, P., SIM, D.S.Y., LIM, S.H., LOW, Y.Y., CHONG, K.W. and LIM, K.H., 2018. Unusual phenethylamine-containing alkaloids from Elaeocarpus tectorius Phytochemistry. 146, 75-81 MEI-KEE LEE, KUAN-HON LIM, PAUL MILLNS, SURESH KUMAR MOHANKUMAR, SZU-TING NG, CHON-SENG TAN, SUE-MIAN THEN and YVONNE MBAKI, 2018. Bronchodilator effects of Lignosus rhinocerotis extract on rat isolated airways is linked to the blockage of calcium entry Phytomedicine. 42, 172-179 MEI-KEE LEE, PAUL MILLNS, YVONNE MBAKI, SZU-TING NG, CHON-SENG TAN, KUAN-HON LIM, SUE-MIAN THEN, SURESH KUMAR MOHANKUMAR and KANG-NEE TING, 2018. Data on the Lignosus rhinocerotis water solublesclerotial extract affecting intracellular calciumlevel in rat dorsal root ganglion cells Data in Brief 18. 1322-1326 SMEDLEY, CHRISTOPHER J., STANLEY, PAUL A., QAZZAZ, MOHANNAD E., PROTA, ANDREA E., OLIERIC, NATACHA, COLLINS, HILARY, EASTMAN, HARRY, BARROW, ANDREW S., LIM, KUAN-HON, KAM, TOH-SEOK, SMITH, BRIAN J., DUIVENVOORDEN, HENDRIKA M., PARKER, BELINDA S., BRADSHAW, TRACEY D., STEINMETZ, MICHEL O. and MOSES, JOHN E., 2018. Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site SCIENTIFIC REPORTS. 8, PREMANAND KRISHNAN, FONG-KAI LEE, KAM-WENG CHONG, CHUN-WAI MAI, AZIRA MUHAMAD, SIEW-HUAH LIM, YUN-YEE LOW, KANG-NEE TING and KUAN-HON LIM, 2018. Alstoscholactine and Alstolaxepine, Monoterpenoid Indole Alkaloids with γ‑Lactone-Bridged Cycloheptane and Oxepane Moieties from Alstonia scholaris Organic Letters. 20, 8014-8018 SOO, HSIEN-CHUEN, CHUNG, FELICIA FEI-LEI, LIM, KUAN-HON, YAP, VERONICA ALICIA, BRADSHAW, TRACEY D., HII, LING-WEI, TAN, SI-HOEY, SEE, SZE-JIA, TAN, YUEN-FEN, LEONG, CHEE-ONN and MAI, CHUN-WAI, 2017. Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway PLOS ONE. 12(1), CHUNG FF, TAN PF, RAJA VJ, TAN BS, LIM KH, KAM TS, HII LW, TAN SH, SEE SJ, TAN YF, WONG LZ, YAM WK, MAI CW, BRADSHAW TD and LEONG CO, 2017. Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1). Scientific reports. 7, 42504 AL-KHDHAIRAWI, AMJAD AYAD QATRAN, KRISHNAN, PREMANAND, MAI, CHUN-WAI, CHUNG, FELICIA FEI-LEI, LEONG, CHEE-ONN, YONG, KIEN-THAI, CHONG, KAM-WENG, LOW, YUN-YEE, KAM, TOH-SEOK and LIM, KUAN-HON, 2017. A Bis-benzopyrroloisoquinoline Alkaloid Incorporating a Cyclobutane Core and a Chlorophenanthroindolizidine Alkaloid with Cytotoxic Activity from Ficus fistulosa var. tengerensis JOURNAL OF NATURAL PRODUCTS. 80(10), 2734-2740 QAZZAZ, M.E., RAJA, V.J., LIM, K.H., KAM, T.S., LEE, J.B., GERSHKOVICH, P. and BRADSHAW, T.D., 2016. In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B. Cancer Letters. 370, 185-197 YAP, V.A., QAZZAZ, M.E., RAJA, V.J., BRADSHAW, T.D., LOH, H.-S., SIM, K.-S., YONG, K.-T., LOW, Y.-Y. and LIM, K.-H., 2016. Fistulopsines A and B antiproliferative septicine-type alkaloids from Ficus fistulosa. Phytochemistry Letters. 15, 136-141 WONG, S.P., CHONG, K.W., LIM, K.H., LIM, S.H., LOW, Y.Y. and KAM, T.S., 2016. Arborisidine and Arbornamine, Two Monoterpenoid Indole Alkaloids with New Polycyclic Carbon-Nitrogen Skeletons Derived from a Common Pericine Precursor ORGANIC LETTERS. 18, 1618-1621 LEE, M.K., TAN, C.S., NG, S.T., LIM, K.H. and TING, K.N., 2016. Lignosus rhinocerotis on Airway Muscle Relaxation In: 19th ISMS Congress, at Amsterdam, The Netherlands.
YAP, V.A., LOONG, B.-J., TING, K.N., LOH, H.-S., YONG, K.-T., LOW, Y.-Y., KAM, T.-S. and LIM, K.-H., 2015. Hispidacine, an unusual 8,4′-oxyneolignan-alkaloid with vasorelaxant activity, and hispiloscine, an antiproliferative phenanthroindolizidine alkaloid, from Ficus hispida Linn. Phytochemistry. 109, 96-102 LIM, K.H., RAJA, V.J., BRADSHAW, T.D., LIM, S.H., LOW, Y.Y. and KAM, T.S., 2015. Ibogan, Tacaman, and Cytotoxic Bisindole Alkaloids from Tabernaemontana. Cononusine, an Iboga Alkaloid with Unusual Incorporation of a Pyrrolidone Moiety Journal of Natural Products. 78(5), 1129-1138 SANTIAGO, C., PANG, E.L., LIM, K.-H., LOH, H.-S. and TING, K.N., 2015. Inhibition of penicillin-binding protein 2a (PBP2a) in methicillin resistant Staphylococcus aureus (MRSA) by combination of ampicillin and a bioactive fraction from Duabanga grandiflora. BMC Complementary and Alternative Medicine. 15, 178 SUET-PICK WONG, CHEW-YAN GAN, KUAN-HON LIM, KANG-NEE TING, YUN-YEE LOW and TOH-SEOK KAM, 2015. Arboridinine, a Pentacyclic Indole Alkaloid with a New Cage Carbon–Nitrogen Skeleton Derived from a Pericine Precursor Organic Letters. 17(14), 3628-3631 LOONG, B.J., TAN, J.H., LIM, K.H., MBAKI, Y. and TING, K.N., 2015. Contractile function of smooth muscle retained after overnight storage Naunyn-Schmiedeberg's Archives of Pharmacology. 388(10), 1061-1067 LIM, S.H., GAN, C.Y., LOW, Y.Y., LIM, K.H. and KAM, T.S., 2015. Lumutinines A-D, Linearly-fused Macroline-Macroline and Macroline-Sarpagine Bisindoles from Alstonia macrophylla In: 5th International Conference for Young Chemists, at Penang, Malaysia.
LOW, Y.Y., HONG, F.J., LIM, K.H., THOMAS, N.F. and KAM, T.S., 2014. Transformations of the 2,7-Seco Aspidosperma alkaloid leuconolam, structure revision of epi-leuconolam, and partial syntheses of leuconoxine and leuconodines A and F. Journal of Natural Products. 77(2), 327-338 RAJA, V.J., LIM, K.H., LEONG, C.O., KAM, T.S. and BRADSHAW, T.D., 2014. Novel antitumour indole alkaloid, Jerantinine A, evokes potent G2/M cell cycle arrest targeting microtubules. Investigational new drugs. 32(5), 838-50 LIM, K.H., KOMIYAMA, K., KAM, T.S., LIM, K.H., THOMAS, N.F. and KAM, T.S., 2012. Perhentidines A-C: Macroline-macroline bisindoles from Alstonia and the absolute configuration of perhentinine and macralstonine Journal of Natural Products. 75, 945-950 WIJAYA, S., TING, K.N., KHOO, T.J., LIM, K.H., LOH, H.S. and WIART, C., 2011. Antibacterial and antioxidant activities of Synedrella nodiflora (L.) Gaertn. (Asteraceae). Journal of Complementary and Integrative Medicine. 8(1), 13 OTHMAN, M., LOH, H.S., WIART, C., KHOO, T.J., LIM, K.H. and TING, K.N., 2011. Optimal methods for evaluating antimicrobial activities from plant extracts. Journal of Microbiological Methods. 84(2), 161-166 LIM, S.W., TING, K.N., BRADSHAW, T., ZEENATHUL, N.A., WIART, C., KHOO, T.J., LIM, K.H. and LOH, H.S., 2011. Acalypha wilkesiana extracts induce apoptosis by causing single strand and double strand DNA breaks Journal of Ethnopharmacology. 138, 616-623 LOW, Y.Y., LIM, K.H., CHOO, Y.M., PANG, H.S., ETOH, T., HAYASHI, M., KOMIYAMA, K. and KAM, T.S., 2010. Structure, biological activity, and biomimetic partial synthesis of the lirofolines, novel pentacyclic indole alkaloids from Tabernaemontana Tetrahedron Letters. 51, 269-272 LIM, K.H., THOMAS, N.F., THOMAS, N.F. and KAM, T.S., 2009. Seco-tabersonine alkaloids from Tabernaemontana corymbosa Phytochemistry. 70, 424-429 LIM, K.H., ETOH, T., HAYASHI, M., LIM, K.H. and KAM, T.S., 2009. Conolutinine, a hexacyclic indole alkaloid with a novel ring system incorporating a diazaspiro center and fused oxadi-azepine-tetrahydrofuran rings Tetrahedron Letters. 50, 752-754 LOW, Y.Y., SUBRAMANIAM, G., LIM, K.H., WONG, R.C.S., ROBINSON, W.T. and KAM, T.S., 2009. Mersiphyllines A and B from Kopsia. Determination of relative configuration at a quaternary center via formation of an alkaloid-borane complex Tetrahedron. 65, 6873-6876 LIM, K.H., LOW, Y.Y., TAN, G.H., KAM, T.S. and LIM, T.M., 2008. Kopsine and danuphylline alkaloids from Kopsia. Biomimetic partial synthesis of danuphylline B. Helvetica Chimica Acta. 91, 1559-1566 LIM, KUAN-HON and KAM, TOH-SEOK, 2008. Some novel biologically active alkaloids from Tabernaemontana and Kopsia In: International Conference on Molecular Chemistry, November 2008, Kuala Lumpur.
LIM, K.H., HIRAKU, O., KOMIYAMA, K. and KAM, T.S., 2008. Jerantinines A-G, cytotoxic Aspidosperma alkaloids from Tabernaemontana corymbosa Journal of Natural Products. 71, 1591-1594 LIM, K.H. and KAM, T.S., 2008. Methyl chanofruticosinate alkaloids from Kopsia arborea. Phytochemistry. 69, 558-561 KAM, TOH-SEOK and LIM, KUAN-HON, 2008. Alkaloids of Kopsia. In: CORDELL, G. A., ed., The Alkaloids: Chemistry and Biology 66. Academic Press: The Netherlands. 1-111 LIM, K.H., HIRAKU, O., KOMIYAMA, K., KOYANO, T., HAYASHI, M. and KAM, T.S., 2007. Biologically active indole alkaloids from Kopsia arborea Journal of Natural Products. 70, 1302-1307 LOW, YUN-YEE, LIM, KUAN-HON and KAM, TOH-SEOK, 2007. Biomimetic oxidative transformations of pericine: Partial synthesis of apparicine and valparicine, a new pentacyclic indole alkaloid from Kopsia In: 12th Asian Chemical Congress, August 2007, Kuala Lumpur.
LIM, K.H. and KAM, T.S., 2007. Secoleuconoxine and oxopericine derivatives from Kopsia. Helvetica Chimica Acta. 90, 31-35 LIM, KUAN-HON and KAM, TOH-SEOK, 2006. Structure, biological activity, and partial synthesis of some novel Kopsia alkaloids In: 22nd Annual Seminar of the Malaysian Natural Product Society and 5th Asian Network of Research on Antidiabetic Plants International Seminar (Oral Presentation), November 2006, Kuala Lumpur.
KAM, T.S., LIM, K.H., YOGANATHAN, K., HAYASHI, M. and KOMIYAMA, K., 2004. Lundurines A-D, cytotoxic indole alkaloids incorporating a cyclopropyl moiety from Kopsia tenuis and revision of the structures of tenuisines A-C Tetrahedron. 60, 10739-10745