University of Nottingham Malaysia
Faculty of Science
     
  
 

Image of Kuan Hon Lim

Kuan Hon Lim

Pharmaceutical Sciences Programme Director,

Contact

  • workRoom B1A03 Block B
    Malaysia Campus
    Jalan Broga
    43500 Semenyih
    Selangor Darul Ehsan
    Malaysia
  • work+6 (03) 8924 8208
  • fax+6 (03) 8924 8018

Teaching Summary

Involved in the teaching of organic chemistry, analytical chemistry and medicinal chemistry to MPharm and Pharmaceutical and Health Sciences (BSc) students:

BP1M01 - The Science of Medicine Manufacture

B31B07 - Pharmaceutical and Biological Chemistry

B31DYS - Dyspepsia

B32AAI - Asthma, Allergies and Immune Diseases (Module Leader for UNMC)

B32C05 - Pharmaceutical Analysis and Spectroscopy (Module Leader)

B32C08 - Laboratory Studies in Pharmaceutical Sciences and Pharmacology

B32C09 - Concepts in Medicinal Chemistry and Drug Discovery (Module Leader)

B33E06 - Medicinal Chemistry and Drug Design

Research Summary

Natural product chemistry and Organic synthesis for structure activity relationship studies

My major research interests focus on discovery of novel natural products from plants, particularly alkaloids and triterpenoids, which possess interesting biological activities. The common activities involved in my research include extraction of plant material, chromatographic isolation of compounds, NMR structure elucidation, chemical modification of natural products, and biological evaluation of pure compounds and derivatives. The various analytical/separation tools employed in my research include NMR, high resolution MS, FT-IR, UV-vis, single crystal X-ray crystallography, circular dichroism, and various chromatographic techniques.

The various plant natural products obtained will be biological evaluated regarding their potential as anticancer, vasorelaxation, and anticholinesterase agents. In cases where potential therapeutic agents were discovered, synthesis and/or semi-synthesis will be carried out to study structure-activity relationships with the aim to uncover analogues with improved biological activity.

Selected Publications

Faculty of Science

University of Nottingham Malaysia
Jalan Broga, 43500 Semenyih
Selangor Darul Ehsan
Malaysia

telephone: +6 (03) 8924 8000
fax: +6 (03) 8924 8018

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